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16(R)-HETE
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
16(R)-HETE图片
CAS NO:183509-22-0
包装与价格:
包装价格(元)
25μg电议
50μg电议
100μg电议

产品介绍
Cas No.183509-22-0
化学名16R-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid
Canonical SMILESCCCCC(O)/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O
分子式C20H32O3
分子量320.5
溶解度0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS (pH 7.2): 0.8 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. 16(S)-HETE inhibits proximal tubule ATPase activity by as much as 60% at a concentration of 2 &#181M.[1]

Reference:
[1]. Carroll, M.A., Balazy, M., Margiotta, P., et al. Cytochrome P-450-d]ependent HETEs: Profile of biological activity and stimulation by vasoactive peptides. American Journal of Physiology 271, R863-R869 (1996).