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12-Deoxywithastramonolide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
12-Deoxywithastramonolide图片
CAS NO:60124-17-6
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
12-Deoxywithastramonolide 是在南非醉茄 (W.
Cas No.60124-17-6
化学名6α,7α-epoxy-5α,22R,27-trihydroxy-1-oxo-ergosta-2,24-dien-26-oic acid δ-lactone
Canonical SMILESCC(C1)=C(CO)C(O[C@@]1([H])[C@@H](C)[C@@]2([H])CC[C@@]3([H])[C@]4([H])[C@H]5[C@H](O5)[C@@]([C@@]6(C)[C@@]4([H])CC[C@@]32C)(O)CC=CC6=O)=O
分子式C28H38O6
分子量470.6
溶解度DMF: 2 mg/ml,DMSO: 0.1 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述 12-Deoxywithastramonolide is a withanolide found in W. somnifera roots. It has anti-inflammatory activity, reducing Tnf-α and increasing Il-10 production in mice following oral administration at doses ranging from 50-200 mg/kg. 12-Deoxywithastramonolide also reduces the growth of A549 lung and HT-29 colorectal cancer cells (IC50s = 47.1 and 29.8 μM, respectively).