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(-)-Voacangarine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(-)-Voacangarine图片
CAS NO:545-84-6
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Cas No.545-84-6
Canonical SMILES[H][C@]12[C@]([C@@H](O)C)([H])C[C@]3([H])C[C@@]1(C(OC)=O)C4=C(C(C=C(OC)C=C5)=C5N4)CC[N@]2C3
分子式C22H28N2O4
分子量384.5
溶解度DMF: 16 mg/ml,DMSO: 16 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.33 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(-)-Voacangarine is an indole alkaloid originally isolated from V. africana that is cytotoxic to HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 cells (IC50s = 20 µg/ml). It is cytostatic to wild-type S. cerevisiae and cytotoxic to δrad3-e5 and δrad6-1 mutant S. cerevisiae, which are defective in DNA strand break repair and the mutagenic repair pathway, respectively.