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(+)-Oxanthromicin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(+)-Oxanthromicin图片
CAS NO:1616622-08-2
包装与价格：
包装价格(元)
250μg电议
1mg电议

产品介绍
Cas No.1616622-08-2
化学名(10R)-10,10'R-dioxybis[9,10-dihydro-3,8-dihydroxy-1,7,10-trimethyl-9-oxo-2-anthracenecarboxylic acid]
Canonical SMILESOC1=C(C(O)=O)C(C)=C2C([C@](OO[C@@]3(C)C(C=CC(C)=C4O)=C4C(C5=C3C=C(O)C(C(O)=O)=C5C)=O)(C)C(C=CC(C)=C6O)=C6C2=O)=C1
分子式C36H30O12
分子量654.6
溶解度DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(+)-Oxanthromicin is an enantiomer of the rare Streptomyces metabolite (-)-oxanthromicin. [1] It inhibits K-Ras plasma membrane localization in MDCK cells with an IC50 value of 62.5 μM.

Referene:
[1]. Salim, A.A., Xiao, X., Cho, K.-J., et al. Rare Streptomyces sp. polyketides as modulators of K-Ras localisation. Org. Biomol. Chem. 12(27), 4872-4878 (2014).