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(+)-Gallocatechin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(+)-Gallocatechin图片
CAS NO:970-73-0
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议

产品介绍
(+)-Gallocatechin 是一种来自绿茶的多酚化合物,具有抗癌活性。
Cas No.970-73-0
别名右旋没食子儿茶素,NSC 674038
化学名(2R,3S)-3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol
Canonical SMILESOC1=CC([C@@H]2[C@@H](O)CC3=C(O)C=C(O)C=C3O2)=CC(O)=C1O
分子式C15H14O7
分子量306.3
溶解度25 mg/ml in DMF, 15 mg/ml in DMSO, 5 mg/ml in ethanol, 1 mg/ml in PBS (pH 7.2)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(+)-Gallocatechin is a polyphenol and flavonoid that has been isolated from the leaves of tea plants and has diverse biological activities. [1] [2] [3] It inhibits the adherence of P. gingivalis onto human buccal epithelial cells by more than 50% when used at a concentration of 250 μg/ml. (+)-Gallocatechin has antimutagenic properties in UV-irradiated E. coli cells. [2] It inhibits cell death induced by D-galactosamine and TNF-α in primary cultured mouse hepatocytes by 29.9% when used at a concentration of 80 μM. [3] (+)-Gallocatechin (100 μM) inhibits HCT116 colorectal cancer cell proliferation by 57%.[1]

Reference:
[1]. Du, G.J., Zhang, Z., Wen, X.D., et al. Epigallocatechin gallate (EGCG) is the most effective cancer chemopreventive polyphenol in green tea. Nutrients 4(11), 1679-1691 (2012).
[2]. Matsuo, T., Hanamure, N., Shimoi, K., et al. Identification of (+)-gallocatechin as a bio-antimutagenic compound in Psidium guava leaves. Phytochemistry 36(4), 1027-1029 (1994).
[3]. Xiong, Q., Fan, W., Tezuka, Y., et al. Hepatoprotective effect of Apocynum venetum and its active constituents. Planta Med. 66(2), 127-133 (2000).
[4]. Sakanaka, S., Aizawa, M., Kim, M., et al. Inhibitory effects of green tea polyphenols on growth and cellular adherence of an oral bacterium, Porphyromonas gingivalis. Biosci. Biotechnol. Biochem. 60(5), 745-749 (1996).