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m-PEG8-azide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
m-PEG8-azide图片
CAS NO:869718-80-9
包装与价格:
包装价格(元)
25mg电议
100mg电议

产品介绍
m-PEG8-azide 是一种基于PEG 的 PROTAC linker,可用于 PROTAC 的合成。
Cas No.869718-80-9
分子式C17H35N3O8
分子量409.48
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

m-PEG8-azide is a PEG-basedPROTAC linkercan be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.