CAS NO: | 119141-88-7 |
包装 | 价格(元) |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Cas No. | 119141-88-7 |
别名 | 埃索美拉唑镁,(S)-Omeprazole; (-)-Omeprazole |
Canonical SMILES | COC1=CC=C2C(N=C([S@](CC3=C(C)C(OC)=C(C)C=N3)=O)N2)=C1 |
分子式 | C17H19N3O3S |
分子量 | 345.4 |
溶解度 | DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Esomeprazole is an inhibitor of the gastric H+/K+-ATPase and the (S) enantiomer of omeprazole .1It reversibly inhibits the activity of the H+/K+-ATPase in an enzyme assay. Esomeprazole (30 mg/kg, s.c.) inhibits histamine-induced gastric acid secretion in rats. Formulations containing esomeprazole in complex with magnesium have been used as proton pump inhibitors (PPIs) in the treatment of gastroesophageal reflux disease (GERD),H. pylorieradication, and hypersecretory conditions, as well as in the prevention of non-steroidal anti-inflammatory drug-related gastric ulcer. 1.Shin, J.M., and Sachs, G.Restoration of acid secretion following treatment with proton pump inhibitorsGastroenterology123(5)1588-1597(2002) |