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trans-carboxy Glimepiride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
trans-carboxy Glimepiride图片
CAS NO:1217739-04-2
包装:1mg
市场价:3402元

产品介绍
A metabolite of glimepiride
Cas No.1217739-04-2
别名格列美脲杂质8
Canonical SMILESO=C(NS(=O)(C1=CC=C(CCNC(N2C(C(CC)=C(C2)C)=O)=O)C=C1)=O)N[C@H]3CC[C@@H](CC3)C(O)=O
分子式C24H32N4O7S
分子量520.6
溶解度DMSO: slightly soluble,Ethyl Acetate: heated, sonicated
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

trans-carboxy Glimepiride is a metabolite of the sulfonylurea glimepiride .1It is formed from glimepiride in a two-step process mediated by the cytochrome P450 (CYP) isoform CYP2C9 and cytosolic enzymes.

1.Noh, K., Kim, E., Jeong, T.C., et al.Simultaneous determination of glimepiride and its metabolites in human plasma by liquid chromatography coupled to a tandem mass spectrometryArch. Pharm. Res.34(12)2073-2078(2011)