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O-Nornuciferine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
O-Nornuciferine图片
CAS NO:3153-55-7
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
O-Noruciferine 是荷叶的一种卟啉型生物碱,是一种有效的 hERG 通道抑制剂。
Cas No.3153-55-7
别名O-去甲荷叶碱
分子式C18H19NO2
分子量281.35
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor[1].

O-Nornuciferine has an IC50 of 7.91 μM in vitro hERG blockages measured in HEK293 cells[1]. O-Nornuciferine (100 μM) has 47% hERG channel inhibition in Xenopus oocytes by lotus alkaloids[1].

[1]. Ulrike Grienke, et al. Human Ether-À-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids From Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements. J Agric Food Chem. 2015 Jun 17;63(23):5634-9.