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Tazofelone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tazofelone图片
CAS NO:107902-67-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
Tazofelone (LY 213829) 是一种环氧合酶-II (COX-II) 抑制剂。Tazofelone 转化为亚砜和喹啉代谢物主要由 CYP3A 介导。Tazofelone 可用于炎症性肠病的研究。
Cas No.107902-67-0
别名LY 213829
分子式C18H27NO2S
分子量321.48
溶解度DMSO : 100 mg/mL (311.06 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tazofelone (LY 213829) is a cyclooxygenase-II (COX-II) inhibitor. Tazofelone transform into sulfoxide and quinol metabolites is primarily mediated by CYP3A. Tazofelone can be used for the research of inflammatory bowel disease[1][2].

[1]. Leopold Franz Goetze,et al. Cox- ii inhibitors for improving reproductive success in a female animal. Patent: WO2007129169 A2.
[2]. Surapaneni SS, et al. In vitro biotransformation and identification of human cytochrome P450 isozyme-dependent metabolism of tazofelone. Drug Metab Dispos. 1997 Dec;25(12):1383-8.