| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| Canonical SMILES | O=C(N[C@H](C(N)=O)CCSC)[C@@H](NC(CNC(CNC([C@@H](N)CC(C=C1)=CC=C1O)=O)=O)=O)CC2=CC=CC=C2.OC(C(F)(F)F)=O |
| 分子式 | C27H36N6O6S • XCF3COOH |
| 分子量 | 572.7 |
| 溶解度 | DMF: 2 mg/ml,DMSO: 10 mg/ml,Ethanol: 3 mg/ml,PBS (pH 7.2): 2 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Met-Enkephalinamide is a peptide opioid receptor agonist and derivative of Met-enkephalin .1,2It binds to opioid receptors in rat cerebellum homogenates (IC50= 0.2 µM) and reduces the twitch height in electrically stimulated isolated guinea pig ileum and isolated mouse vas deferens. Met-Enkephalinamide (300 µg/animal) induces analgesia in the hot plate and tail-flick tests in rats, effects that can be reversed by administration of the opioid receptor antagonist naloxone.3 1.Change, J.-K., and Fong, B.T.W.Opiate receptor affinities and behavioral effects of enkephalin: Structure-activity relationship of ten synthetic peptide analoguesLife Sci.18(12)1473-1481(1976) 2.Quinn, M.J., Laska, F.J., and Fennessy, M.R.Structure-activity relationships of met5- and leu5-enkephalin analoguesClin. Exp. Pharmacol. Physiol.6535-540(1979) 3.Yaksh, T.L., Huang, S.P., and Rudy, T.A.The direct and specific opiate-like effect of Met5-enkephalin and analogues on the spinal cordNeuroscience2(4)593-596(1977) |
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