CAS NO: | 1213669-91-0 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
Cas No. | 1213669-91-0 |
Canonical SMILES | CN1C(COC2=NN3C(C4=C(C=CC(F)=C4)F)=NN=C3C=C2C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=NC=N1 |
分子式 | C19H10D9F2N7O |
分子量 | 408.5 |
溶解度 | DMF: 3 mg/ml,DMSO: 3 mg/ml,Ethanol: 2 mg/ml,PBS (pH 7.2): insol |
储存条件 | -20буC |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | CTP354 is a deuterated derivative of the GABAAreceptor modulator L-838,417.1It binds to the GABAAreceptor benzodiazepine binding site in non-α1subunit-containing GABAAreceptors. CTP354 has a longer duration of action than L-838,417 in a rat model of neuropathic pain induced by sciatic nerve ligation. 1.Harbeson, S.L., and Tung, R.D.Deuterium medicinal chemistry: A new approach to drug discovery and developmentMedchem News24(2)8-22(2014) |