| CAS NO: | 116569-09-6 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| Cas No. | 116569-09-6 |
| 别名 | 5-羟基靛红 |
| Canonical SMILES | O=C1NC2=CC=C(C=C2C1=O)O |
| 分子式 | C8H5NO3 |
| 分子量 | 163.1 |
| 溶解度 | DMF: 3 mg/ml,DMSO: 5 mg/ml,Ethanol: insol,PBS (pH 7.2): insol |
| 储存条件 | -20буC |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 5-hydroxy Isatin is an inhibitor of monoamine oxidase A (MAO-A; IC50= 8.4 µM).1It is selective for MAO-A over MAO-B (IC50= >100 µM). 5-hydroxy Isatin (50 µM) also inhibits atrial natriuretic peptide-induced activation of particulate guanylyl cyclase in rat brain and heart membranes.2 1.Medvedev, A.E., Goodwin, B., Chow, A., et al.Inhibitory potency of some isatin analogues on human monoamine oxidase A and BBiochem. Pharmacol.44(3)590-592(1992) 2.Medvedev, A.E., Goodwin, B.L., Sandler, M., et al.Efficacy of isatin analogues as antagonists of rat brain and heart atrial natriuretic peptide receptors coupled to particulate guanylyl cyclaseBiochem. Pharmacol.57(8)913-915(1999) |
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