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6β-hydroxy Eplerenone
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
6β-hydroxy Eplerenone图片
CAS NO:209253-80-5
包装:1mg
市场价:6426元

产品介绍
A major metabolite of eplerenone
Cas No.209253-80-5
别名依普利酮6-BETA-羟基类似物
Canonical SMILESO=C1CC[C@@]2(C)C([C@H](O)[C@@H](C(OC)=O)[C@]3([H])[C@]2(O4)[C@H]4C[C@@]5(C)[C@@]3([H])CC[C@]56OC(CC6)=O)=C1
分子式C24H30O7
分子量430.5
溶解度Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone .1 It is formed from eplerenone by the cytochrome P450 (CYP) isoform CYP3A4.

|1. Cook, C.S., Berry, L.M., Kim, D.H., et al. Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: Differential metabolism by CYP3A4 and CYP3A5. Drug Metab. Dispos. 30(12), 1344-1351 (2002).