CAS NO: | 1246833-81-7 |
包装: | 1mg |
市场价: | 3462元 |
Cas No. | 1246833-81-7 |
别名 | 盐酸萘替芬 d3 (盐酸盐) |
Canonical SMILES | [2H]C([2H])([2H])N(C/C=C/C1=CC=CC=C1)CC2=C(C=CC=C3)C3=CC=C2.Cl |
分子式 | C21H18D3N.HCl |
分子量 | 326.9 |
溶解度 | DMF: 10 mg/ml,DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml,DMSO: 5 mg/ml,Ethanol: 5 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Naftifine-d3 is intended for use as an internal standard for the quantification of naftifine by GC- or LC-MS. Naftifine is an allylamine compound that blocks ergosterol biosynthesis in fungi by inhibiting squalene epoxidase (Ki = 1.1 μM for C. albicans epoxidase).1 |1. Ryder, N.S., and Dupont, M.C. Inhibition of squalene epoxidase by allylamine antimycotic compounds. A comparative study of the fungal and mammalian enzymes. Biochem. J. 230(3), 765-770 (1985). |