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Apalutamide D4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Apalutamide D4图片
CAS NO:1638885-65-0
包装:1mg
市场价:3780元

产品介绍
ApalutamideD4(ARN-509D4)是Apalutamide的一种氘代化合物。Apalutamide是有效,竞争性的雄激素受体(AR)拮抗剂,IC50为16nM。
Cas No.1638885-65-0
别名ARN-509-d4
Canonical SMILESO=C(NC)C1=CC=C(N(C(N(C2=CC(C(F)(F)F)=C(C#N)N=C2)C3=O)=S)C43C([2H])([2H])CC4([2H])[2H])C=C1F
分子式C21H11D4F4N5O2S
分子量481.46
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Apalutamide D4 (ARN-509 D4) is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].

[1]. Clegg NJ, et al. ARN-509: a novel antiandrogen for prostate cancer treatment. Cancer Res. 2012 Mar 15;72(6):1494-503.