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17β-Estradiol-d2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
17β-Estradiol-d2图片
CAS NO:53866-33-4
包装与价格:
包装价格(元)
500 μg电议
1mg电议
5mg电议

产品介绍
1&7#946;-Estradiol-d2 (β-1&7#946;-Estradiol-d2) 是氘标记的雌二醇。
Cas No.53866-33-4
别名BETA-雌二醇-D2,β-Estradiol-d2; 17β-Estradiol-d2; 17β-Oestradiol-d2
Canonical SMILESOC1=C([2H])C=C2C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4O)=C1[2H]
分子式C18H22D2O2
分子量274.4
溶解度DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS(pH 7.2) (1:4): 0.2 mg/ml,Ethanol: 2 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

17β-Estradiol-d2is intended for use as an internal standard for the quantification of 17β-estradiol by GC- or LC-MS. 17β-Estradiol is the major estrogen secreted by the premenopausal ovary. It is synthesized from testosterone primarily in the ovarian granulosa cells and placenta, but small amounts can be produced in the adrenal gland.1,2Plasma 17β-estradiol levels increase gradually between days 1-7 of the menstrual cycle followed by a sharp increase to a peak value of about 300 pg/ml on day 12, just prior to ovulation.3,4

1.Vance, D.E.Cholesterol and related derivativesBiochemistry2nd ed.725-748(1988) 2.Miller, W.L., and Tyrrell, J.B.The adrenal cortexEndocrinology and Metabolism3rd edition555-711(1995) 3.Erickson, G.F.The ovary: Basic principles and concepts. A. PhysiologyEndocrinology and Metabolism3rd ed.973-1015(1995) 4.Munro, C.J., Stabenfeldt, G.H., Cragun, J.R., et al.Relationship of serum estradiol and progesterone concentrations to the excretion profiles of their major urinary metabolites as measured by enzyme immunoassay and radioimmunoassayClin. Chem.37(6)838-844(1991)