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Mometasone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mometasone图片
CAS NO:105102-22-5
包装与价格:
包装价格(元)
500 μg电议
1mg电议

产品介绍
莫米松是一种吸入性糖皮质激素。
Cas No.105102-22-5
别名莫米松-d3EP杂质G)
Canonical SMILESCl[C@@]12[C@](CCC([C@@]2(C=C3)C)=CC3=O)([H])[C@@]4([H])[C@](C[C@@H]1O)([C@](C(CCl)=O)(O)[C@@H](C4)C)C
分子式C22H28Cl2O4
分子量427.4
溶解度Methanol: Slightly soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Mometasone is a synthetic glucocorticoid with anti-inflammatory and anti-allergic activities.1,2,3In vivo, mometasone (3 mg/kg) reduces pulmonary edema and neutrophil infiltration in a mouse model of chlorine-induced chemical lung injury.1Intranasal administration of mometasone (0.2 µg/animal) reduces nose-rubbing behavior, sneezing, and nasal mucosal levels of IL-4 in a mouse model of allergic rhinitis.2Mometasone also reduces nasal mucosal epithelial destruction, fibrosis, and cilia loss in a rat model of rhinitis medicamentosa induced by oxymetazoline .

1.Kitlevsen, D.K., Povlsen, G.K., Berezin, V., et al.NCAM-induced intracellular signaling revisitedJ. Neurosci. Res.86(4)727-743(2008) 2.Williams, E.J., Furness, J., Walsh, F.S., et al.Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherinNeuron.13(3)583-594(1994) 3.Van Acker, H.H., Van Acker, Z.P., Versteven, M., et al.CD56 homodimerization and participation in anti-tumor immune effector cell functioning: A role for interleukin-15Cancers (Basel)11(7)1029(2019)