| CAS NO: | 51938-11-5 |
| 包装: | 2.5mg |
| 市场价: | 3916元 |
| Cas No. | 51938-11-5 |
| Canonical SMILES | ClC1=CC=C2SC3=CC(O)=CC=C3N(CCCN(C)C)C2=C1.Cl |
| 分子式 | C17H19ClN2OS•HCl |
| 分子量 | 371.3 |
| 溶解度 | Methanol: slightly soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 7-hydroxy Chlorpromazine is an active metabolite of the typical antipsychotic chlorpromazine .1In vivo, 7-hydroxy chlorpromazine (5 mg/kg) increases plasma prolactin levels in male rats. It also reverses D-amphetamine-induced depression of the dopaminergic neuronal firing rate in the rat substantia nigra in rats when administered at a dose of 1.6 mg/kg.2 1.Meltzer, H.Y., Fang, V.S., Simonovich, M., et al.Effect of metabolites of chlorpromazine on plasma prolactin levels in male ratsEur. J. Pharmacol.41(4)431-436(1977) 2.Bunney, B.S., and Aghajanian, G.K.A comparison of the effects of chlorpromazine, 7-hydroxychlorpromazine and chlorpromazine sulfoxide on the activity of central dopaminergic neuronsLife Sci.15(2)309-318(1974) |
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