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7α-hydroxy Dehydroepiandrosterone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
7α-hydroxy Dehydroepiandrosterone图片
CAS NO:53-00-9
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍

An active metabolite of dehydroepiandrosterone

Cas No.53-00-9
别名7-羟基去氢表雄酮
Canonical SMILESC[C@@]12[C@]3([H])[C@]([C@@H](C=C1C[C@H](CC2)O)O)([H])[C@@]4([H])[C@](CC3)(C(CC4)=O)C
分子式C19H28O3
分子量304.4
溶解度Ethanol: soluble
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

7α-hydroxy Dehydroepiandrosterone (7α-hydroxy DHEA) is an active metabolite of the endogenous steroid hormone dehydroepiandrosterone .17α-hydroxy DHEA is formed from dehydroepiandrosteronevia7-hydroxylation by cytochrome P450s (CYPs).2It increases antigen-induced production of anti-tetanus toxoid and anti-pertussis antigen IgGs in co-cultures of human tonsil-derived B and T cells when used at a concentration of 1 &#181M.37α-hydroxy DHEA (6.25 mg/kg) increases serum concentrations of anti-lysozyme IgG in mice.1

1.Morfin, R., and Courchay, G.Pregnenolone and dehydroepiandrosterone as precursors of native 7-hydroxylated metabolites which increase the immune response in miceJ. Steroid Biochem. Mol. Biol.50(1-2)91-100(1994) 2.Hampl, R., Morfin, R., and Starka, L.7-Hydroxylated derivatives of dehydroepiandrosterone: What are they good foroEndocr. Regul.31(4)211-218(1997) 3.Lafaye, P., Chmielewski, V., Nato, F., et al.The 7α-hydroxysteroids produced in human tonsils enhance the immune response to tetanus toxoid and Bordetella pertussis antigensBiochim. Biophys. Acta1472(1-2)222-231(1999)