| CAS NO: | 5226-01-7 |
| 包装: | 1mg |
| 市场价: | 1620元 |
| Cas No. | 5226-01-7 |
| Canonical SMILES | C[C@@]12[C@](CC[C@]2([H])[C@@H](CCCC(C)C)C)([H])C3=CC=C(C[C@H](CC4)O)[C@]4(C)[C@]3([H])CC1 |
| 分子式 | C27H44O |
| 分子量 | 384.6 |
| 溶解度 | Chloroform: slightly soluble,Methanol: slightly soluble |
| 储存条件 | -80°C,unstable in solution, ready to use. |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Lumisterol 3 (L3) is a photoisomer of previtamin D3.1It is formed by photoisomerization of previtamin D3in the epidermis by prolonged UVB exposure and is metabolized by the cytochrome P450 (CYP) isoform CYP11A1 in a variety of tissues to several hydroxylated metabolites, including the active metabolites 20-hydroxy L3, 24-hydroxy L3, and 20,22-dihydroxy L3.2,3 1.Slominski, A.T., Chaiprasongsuk, A., Janjetovic, Z., et al.Photoprotective droperties of vitamin D and lumisterol hydroxyderivativesCell Biochem. Biophys.78(2)165-180(2020) 2.Holick, M.F.Photosynthesis of vitamin D in the skin: Effect of environmental and life-style variablesFed. Proc.46(5)1876-1882(1987) 3.Slominski, A.T., Kim, T.-K., Hobrath, J.V., et al.Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterolsSci. Rep.7(1)11434(2017) |
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