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2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline图片
CAS NO:77094-11-2
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
A mutagenic heterocyclic amine
Cas No.77094-11-2
别名2-氨基-3,4-二甲基-3H-咪唑并喹啉
Canonical SMILESNC(N1C)=NC2=C1C(C)=CC3=C2C=CC=N3
分子式C12H12N4
分子量212.3
溶解度Methanol: Slightly Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline is a mutagenic heterocyclic amine that has been found in cooked foods.1,2,3It is mutagenic toS. typhimuriumin the Ames test.3Dietary administration of 2-amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline (0.03%) induces tumor formation in the Zymbal gland, oral cavity, and colon in male and female rats, the skin of male rats, and the mammary gland in female rats.1

1.Kato, T., Migita, H., Ohgaki, H., et al.Induction of tumors in the Zymbal gland, oral cavity, colon, skin and mammary gland of F344 rats by a mutagenic compound, 2-amino-3,4-dimethylimidazo[4,5-f]quinolineCarcinogenesis19(3)601-603(1989) 2.Johansson, M.A., and JÄgerstad, M.Occurrence of mutagenic/carcinogenic heterocyclic amines in meat and fish products, including pan residues, prepared under domestic conditionsCarcinogenesis15(8)1511-1518(1994) 3.Nagao, M., Sato, S., and Sugimura, T.Mutagens produced by heating foodsThe Maillard reaction in foods and nutrition521-536(1983)