| CAS NO: | 131341-86-1 |
| 包装 | 价格(元) |
| 50mg | 电议 |
| 100mg | 电议 |
| Cas No. | 131341-86-1 |
| 别名 | 咯菌腈 |
| Canonical SMILES | FC1(F)OC2=CC=CC(C3=CNC=C3C#N)=C2O1 |
| 分子式 | C12H6F2N2O2 |
| 分子量 | 248.2 |
| 溶解度 | DMSO: Slightly Soluble,Methanol: Slightly Soluble |
| 储存条件 | Store at -20°C, filled inert atmosphere |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Fludioxonil is a phenylpyrrole fungicide.1It inhibits the growth ofB. cinereaisolates from strawberry and blackberry crops (EC50s = 0.06-0.38 mg/L).2Fludioxonil also inhibits the growth ofS. cerevisiaeAF293 andC. albicansIFO1385 in a concentration-dependent manner.1,3It is an estrogen receptor α (ERα) agonist (EC50= 3.7 μM in a yeast reporter assay) that induces expression of the oncogenic microRNA miR-21, inhibits estradiol-induced proliferation, and reduces cell motility of MCF-7 breast cancer cellsin vitro.4 1.Kim, J.H., Campbell, B.C., Mahoney, N., et al.Enhanced activity of strobilurin and fludioxonil by using berberine and phenolic compounds to target fungal antioxidative stress responseLett. Appl. Microbiol.45(2)134-141(2007) 2.Li, X., FernÁndez-OrtuÑo, D., Grabke, A., et al.Resistance to fludioxonil in Botrytis cinerea isolates from blackberry and strawberryPhytopathology104(7)724-732(2014) 3.Ochiai, N., Fujimura, M., Oshima, M., et al.Effects of iprodione and fludioxonil on glycerol synthesis and hyphal development in Candida albicansBiosci. Biotechnol. Biochem.66(10)2209-2215(2002) 4.Teng, Y., Manavalan, T.T., Hu, C., et al.Endocrine disruptors fludioxonil and fenhexamid stimulate miR-21 expression in breast cancer cellsToxicol. Sci.131(1)71-83(2013) |
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