| CAS NO: | 115970-66-6 |
| 包装 | 价格(元) |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| Cas No. | 115970-66-6 |
| Canonical SMILES | ClC1=C(CCC/C1=C\C=C2C(C)(C)C3=CC=CC=C3N\2CCCCS([O-])(=O)=O)/C=C/C4=[N+](CCCCS([O-])(=O)=O)C5=CC=CC=C5C4(C)C.[Na+] |
| 分子式 | C38H46ClN2O6S2•Na |
| 分子量 | 749.4 |
| 溶解度 | DMF: 1 mg/ml,DMSO: 1 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 1 mg/ml |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | IR 783 is a heptamethine cyanine fluorescent probe forin vivoimaging of tumor cells.1,2It displays excitation/emission maxima of 633/780 nm, respectively. IR 783 is transported into tumor cells, an effect that can be blocked by the organic anion transporting polypeptide (OATP) inhibitor sulfobromophthalein .1In vivo, IR 783 (11.25 mg/kg) preferentially accumulates in tumor tissue in an ACHN kidney cancer mouse xenograft model.2It has been conjugated to polyethylenimines for tumor-specific gene delivery.3 1.Yuan, J., Yi, X., Yan, F., et al.Near?infrared fluorescence imaging of prostate cancer using heptamethine carbocyanine dyesMol. Med. Rep.11(2)821-828(2015) 2.Yang, X., Shao, C., Wang, R., et al.Optical imaging of kidney cancer with novel near-infrared heptamethine carbocyanine fluorescent dyesJ. Urol.189(2)702-710(2013) 3.De Los Reyes-Berbel, E., Salto-Gonzalez, R., Ortega-MuÑoz, M., et al.PEI-NIR heptamethine cyanine nanotheranostics for tumor targeted gene deliveryBioconjug. Chem.29(8)2561-2575(2018) |
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