| CAS NO: | 178182-49-5 |
| 包装: | 1mg |
| 市场价: | 9813元 |
| Cas No. | 178182-49-5 |
| Canonical SMILES | O[C@@H]1CC2=CC3=C(C(OC(C(OC)=O)=C3)=O)C(O)=C2O[C@@]14OC5=C(O)C(C(C(OC)=CC6=O)=O)=C6C(O)=C5[C@H]4O[C@H]7C[C@@H](OC)[C@@H](O)[C@H](C)O7 |
| 分子式 | C33H30O17 |
| 分子量 | 698.6 |
| 储存条件 | 4°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Heliquinomycin is a bacterial metabolite originally isolated fromStreptomycesthat has diverse biological activities.1It is active against a variety of Gram-positive bacteria, including strains ofB. anthracis, B. subtilis, and methicillin-sensitive or -resistantS. aureus(MICs =<0.05-0.39 µg/ml). Heliquinomycin inhibits the activity of DNA helicase with a Kivalue of 6.8 µM. It reduces the growth of L1210 leukemia, B16 melanoma, and FS-3 fibrosarcoma cells (IC50s = 0.97, 0.89, and 0.83 µg/ml, respectively). 1.Chino, M., Nishikawa, K., Umekita, M., et al.Heliquinomycin, a new inhibitor of DNA helicase, produced by Streptomyces sp. MJ929-SF2 I. Taxonomy, production, isolation, physico-chemical properties and biological activitiesJ. Antibiot. (Tokyo)49(8)752-757(1996) |
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