CAS NO: | 269741-97-1 |
包装 | 价格(元) |
250µg | 电议 |
1mg | 电议 |
Cas No. | 269741-97-1 |
别名 | (+)-Avrainvillamide; CJ-17,665 |
Canonical SMILES | O=C1[C@@](C=C(C2=CC=C3C(C=CC(C)(C)O3)=C24)C5=[N]4=O)(NC6=O)[C@@](C5(C)C)([H])CC76N1CCC7 |
分子式 | C26H27N3O4 |
分子量 | 445.5 |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Avrainvillamide is a fungal metabolite and monomeric form of stephacidin B that has been found inA. ochraceus.1,2It is active againstS. aureus,S. pyogenes, andE. faecalis(MICs = 12.5, 12.5, and 25 µg/ml, respectively).2Avrainvillamide inhibits the growth of LNCaP, BT-549, T47D, and MALME-3M cancer cells with GI50values of 0.24, 0.62, 0.21, and 0.41 µM, respectively.1 1.Wulff, J.E., Herzon, S.B., Siegrist, R., et al.Evidence for the rapid conversion of stephacidin B into the electrophilic monomer avrainvillamide in cell cultureJ. Am. Chem. Soc.129(16)4898-4899(2007) 2.Sugie, Y., Hirai, H., Inagaki, T., et al.A new antibiotic CJ-17,665 from Aspergillus ochraceusJ. Antibiot.54(11)911-916(2001) |