| CAS NO: | 863394-07-4 |
| 包装 | 价格(元) |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| Cas No. | 863394-07-4 |
| Canonical SMILES | C[Se]C[C@H](N)C(O)=O.Cl |
| 分子式 | C4H9NO2Se •HCl |
| 分子量 | 218.6 |
| 溶解度 | DMF: 1 mg/ml,DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Se-Methylselenocysteine is a selenium-containing amino acid that has been found inAlliumand has antioxidative and anticancer augmenting activities.1,2Se-Methylselenocysteine (0.01-10 µM) preventstert-butyl hydroperoxide-induced increases in malondialdehyde (MDA) levels and glutathione reductase and glutathione peroxidase (GPX) activity, as well as decreases in glutathione (GSH) levels, in HepG2 cells.1It has an additive effect on irinotecan-induced tumor growth reduction in a FaDu mouse xenograft model when administered at a dose of 5 µg/animal per day.2 1.Cuello, S., Ramos, S., Mateos, R., et al.Selenium methylselenocysteine protects human hepatoma HepG2 cells against oxidative stress induced by tert-butyl hydroperoxideAnal. Bioanal. Chem.389(7-8)2167-2178(2007) 2.Azrak, R.G., Cao, S., Pendyala, L., et al.Efficacy of increasing the therapeutic index of irinotecan, plasma and tissue selenium concentrations is methylselenocysteine dose dependentBiochem. Pharmacol.73(9)1280-1287(2007) |
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