| CAS NO: | 1215507-88-2 |
| 包装 | 价格(元) |
| 500 µg | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 1215507-88-2 |
| Canonical SMILES | [2H]C([2H])([2H])NCC(C1=CC(OC)=C(C=C1)O)O.Cl |
| 分子式 | C10H12D3NO3·HCl |
| 分子量 | 236.7 |
| 溶解度 | DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml,PBS (pH 7.2): 15 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Metanephrine-d3is intended for use as an internal standard for the quantification of metanephrine by GC- or LC-MS. Metanephrine is an inactive metabolite of epinephrine .1It is formed from epinephrine by catechol-O-methyl transferase (COMT).2Urinary and plasma levels of metanephrine are increased in patients with pheochromocytoma, an adrenal medullary neuroendocrine tumor.3,4 1.Bilezikian, J.P., Dornfeld, A.M., and Gammon, D.E.Structure-binding-activity analysis of beta-adrenergic amines—I. Binding to the beta receptor and activation of adenylate cyclaseBiochem. Pharmacol.27(10)1445-1454(1978) 2.Kopin, I.J., Axelrod, J., and Gordon, E.The metabolic fate of H3-epinephrine and C14-metanephrine in the ratJ. Biol. Chem.236(7)2109-2136(1961) 3.Wolthers, B.G., Kema, I.P., Volmer, M., et al.Evaluation of urinary metanephrine and normetanephrine enzyme immunoassay (ELISA) kits by comparison with isotope dilution mass spectrometryClin. Chem.43(1)114-120(1997) 4.Goldstein, D.S., Eisenhofer, G., and Kopin, I.J.Sources and significance of plasma levels of catechols and their metabolites in humansJ. Pharm. Exp. Ther.305(3)800-811(2003) |
m.cnreagent.com