CAS NO: | 77058-74-3 |
包装: | 1mg |
市场价: | 1134元 |
Cas No. | 77058-74-3 |
别名 | (24S)-24,25-环氧胆固醇,24(S)-24,25-EC |
化学名 | (3β,24S)-24,25-epoxy-cholest-5-en-3-ol |
Canonical SMILES | CC1(C)[C@H](CC[C@@H](C)[C@@]2([H])CC[C@@]3([H])[C@]4([H])CC=C5C[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@@]32C)O1 |
分子式 | C27H44O2 |
分子量 | 400.6 |
溶解度 | Soluble in ethanol |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain. [1] It activates liver X receptors (LXRs) in the developing ventral midbrain to induce stem cell differentiation into dopaminergic neurons. 24(S),25-epoxy Cholesterol inhibits IL-6 production and degranulation of bone marrow-derived murine mast cells that express LXRβ.[2] It inhibits the conversion of demosterol to cholesterol by 3β-hydroxysterol δ24-reductase (DHCR24/Seladin-1) in CHO-7 and SRD-1 cells when used at a concentration of 2.5 μM. [3] Reference: |