Cas No. | 125-04-2 |
别名 | 氢化可的松琥珀酸钠 |
Canonical SMILES | [H][C@]12[C@@]([C@@](CC[C@]3(O)C(COC(CCC([O-])=O)=O)=O)([H])[C@]3(C)C[C@@H]2O)([H])CCC4=CC(CC[C@@]41C)=O.[Na+] |
分子式 | C25H33O8•Na |
分子量 | 484.5 |
溶解度 | ≤20mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol. It can bind to glucocorticoid receptors, initiating the transcription of anti-inflammatory and immunosuppressive mediators and inhibiting proinflammatory cytokine activity (IC50 = 6.7 µM for IL-6). It is commonly used to supplement media for long-term epithelial or endothelial cell cultures and to differentiate pluripotent stem cells. |