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Foxy-5
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Foxy-5图片
CAS NO:881188-51-8
包装:1mg
市场价:2043元

产品介绍
Foxy-5 是一种 Wnt 家族的非典型成员 WNT5A 的模拟肽。Foxy-5 是一种 WNT5A 激动剂，在原位小鼠模型中能有效降低 WNT5A 低表达的前列腺癌细胞的转移扩散。
Cas No.881188-51-8
别名N-甲酰-L-甲酰-L-Α-天冬氨酸-甘氨酸-L-胱氨酸-L-Α-谷氨酰胺-L-亮氨酸
分子式C26H42N6O12S2
分子量694.77
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Foxy-5 is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family. Foxy-5 is a WNT5A agonist and effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model[1][2]. WNT5A[1]

Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model[1].Foxy-5 reduces the number of colonic cancer stem cells in a xenograft mouse model of human colonic cancer[2].

[1]. Canesin G, et al. Treatment with the WNT5A-mimicking peptide Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model. PLoS One. 2017 Sep 8;12(9):e0184418. [2]. Osman J, et al. The WNT5A Agonist Foxy5 Reduces the Number of Colonic Cancer Stem Cells in a Xenograft Mouse Model of Human Colonic Cancer. Anticancer Res. 2019 Apr;39(4):1719-1728.