CAS NO: | 946002-48-8 |
包装: | 10mg |
市场价: | 4307元 |
Cas No. | 946002-48-8 |
Canonical SMILES | COC1=C(CN([C@@H]2CC[C@@H](NC)CC2)C(C3=C(Cl)C4=C(C(F)=CC=C4F)S3)=O)C=C(C5=CC=NC=C5)C=C1 |
分子式 | C29H28ClF2N3O2S |
分子量 | 556.07 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Potent Hedgehog signaling activator (EC50 = 0.4 nM). Orally bioavailable and brain penetrant. Brunton et al (2009) Potent agonists of the Hedgehog signaling pathway. Bioorg.Med.Chem.Lett. 19 4308 PMID:19500978 |