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KRAS G12C inhibitor 14
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
KRAS G12C inhibitor 14图片
CAS NO:2349393-95-7
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
KRAS G12C inhibitor 14 是一种有效的 KRAS G12C 抑制剂,IC50 为 18 nM,详细信息请参考专利文献 WO2019110751A1 中的化合物 17。
Cas No.2349393-95-7
分子式C24H19ClF2N4O3
分子量484.88
溶解度DMSO : 100 mg/mL (206.24 mM; Need ultrasonic)
储存条件Store at -20°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 17, has an IC50 of 18 nM[1].

[1]. Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.