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AGI-41998
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AGI-41998图片
CAS NO:2377492-26-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
AGI-41998 是一种有效的蛋氨酸腺苷转移酶 2A (MAT2A) 抑制剂。AGI-41998 是一种脑渗透化合物。AGI-41998 具有探索 SAM 调节在中枢神经系统 (CNS) 中的作用和癌症疾病研究的潜力。
Cas No.2377492-26-5
分子式C22H16BrF3N4O2
分子量505.29
溶解度DMSO : 83.33 mg/mL (164.92 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

AGI-41998 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A). AGI-41998 is a brain-penetrant compound. AGI-41998 has the potential for exploring the effects of SAM modulation in the central nervous system (CNS) and research of cancer disease[1].

[1]. Li M, et al. Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. J Med Chem. 2022;65(6):4600-4615.