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Penehyclidine hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Penehyclidine hydrochloride图片
CAS NO:151937-76-7
包装:5mg
市场价:4950元

产品介绍
Penehyclidine (Penequinine) hydrochloride 是一种抗胆碱能药物,选择性的 M1 和 M3 受体拮抗剂。Penehyclidine hydrochloride 可激活肺组织中的 NF-kβ 并抑制炎症因子的释放。Penehyclidine hydrochloride 可减轻慢性阻塞性肺病 (COPD) 大鼠机械通气时的肺部炎症反应。
Cas No.151937-76-7
别名盐酸戊乙奎醚(同分异构体混合物),Penequinine hydrochloride
分子式C20H30ClNO2
分子量351.91
储存条件-20°C, away from moisture
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Penehyclidine (Penequinine) hydrochloride, a anticholinergic drug, is a selective antagonist of M1 and M3 receptors. Penehyclidine hydrochloride activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine hydrochloride can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation[1].

[1]. Zhi-Yuan Chen, et al. The Mechanism of Penehyclidine Hydrochloride and Its Effect on the Inflammatory Response of Lung Tissue in Rats with Chronic Obstructive Pulmonary Disease During Mechanical Ventilation. Int J Chron Obstruct Pulmon Dis. 2021 Mar 31;16:877-885.