P11 是整合素 αvβ3-玻连蛋白相互作用的拮抗剂,IC50 为 1.74 pg/mL (2.414 pM)。
Cas No. | 848644-86-0 |
化学名 | (S,Z)-4-(((S,Z)-1-(((S,Z)-1-(((S)-6-amino-1-hydroxy-1-iminohexan-2-yl)imino)-1-hydroxy-3-(1H-imidazol-5-yl)propan-2-yl)imino)-1-hydroxy-3-methylbutan-2-yl)imino)-3-((Z)-((S)-2-((Z)-((S)-2-amino-1-hydroxy-3-(1H-imidazol-5-yl)propylidene)amino)-1,3-dihydrox |
Canonical SMILES | CC([C@@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](N)([H])CC1=CN=CN1)([H])CO)([H])CC(O)=O)([H])/C(O)=N/[C@@](/C(O)=N/[C@@](C(O)=N)([H])CCCCN)([H])CC2=CN=CN2)C |
分子式 | C30H48N12O9 |
分子量 | 720.78 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml |
储存条件 | -20°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |