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Gly-Arg-Gly-Asp-Ser
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Gly-Arg-Gly-Asp-Ser图片
CAS NO:96426-21-0
包装与价格：
包装价格(元)
2mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Gly-Arg-Gly-Asp-Ser是一种五肽，构成了糖蛋白，骨桥蛋白与细胞的结合域。
Cas No.96426-21-0
Canonical SMILESGly-Arg-Gly-Asp-Ser
分子式C17H30N8O9
分子量490.47
溶解度DMSO : 100 mg/mL (203.89 mM);Water : 33.33 mg/mL (67.96 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Gly-Arg-Gly-Asp-Ser is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin.

Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3, with IC50 of 5 μM[1]. GRGDS-immobilized TiO2 nanotubes enhance osteoblast-like cell (MG-63) adhesion, and significantly increased cell spreading and proliferation[2].

[1]. Bernhagen D, et al. High-Affinity RGD-Knottin Peptide as a New Tool for Rapid Evaluation of the Binding Strength of Unlabeled RGD-Peptides to αvβ3, αvβ5, and α5β1 Integrin Receptors. Anal Chem. 2017 Jun 6;89(11):5991-5997. [2]. Kim GH, et al. Evaluation of Osteoblast-Like Cell Viability and Differentiation on the Gly-Arg-Gly-Asp-Ser Peptide Immobilized Titanium Dioxide Nanotube via Chemical Grafting. J Nanosci Nanotechnol. 2016 Feb;16(2):1396-9.