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Protease-Activated Receptor-4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Protease-Activated Receptor-4图片
CAS NO:245443-52-1
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
Protease-ActivatedReceptor-4是转化生长因子受体4的激动剂。
Cas No.245443-52-1
别名蛋白酶活化的受体-4
Canonical SMILESGly-Tyr-Pro-Gly-Lys-Phe-NH2
分子式C33H46N8O7
分子量666.77
溶解度Water : 50 mg/mL (74.99 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4).

GYPGKF-NH2 significantly reduces the agonistic potency of AYPGKF-NH2 by 25-fold[1]. GYPGKF-NH2 (500 μM) does not cause contraction or relaxation of the guinea pig IAS strips[2].

[1]. Moschonas IC, et al. Molecular requirements involving the human platelet protease-activated receptor-4 mechanism of activation by peptide analogues of its tethered-ligand. Platelets. 2017 Mar 7:1-10. doi: 10.1080/09537104.2017.1282607. [Epub ahead of print] [2]. Huang SC, et al. Proteinase-activated receptor-1 (PAR1) and PAR2 mediate relaxation of guinea pig internal anal sphincter. Regul Pept. 2014 Feb 10;189:46-50.