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Sucrose octasulfate(potassium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sucrose octasulfate(potassium salt)图片
CAS NO:73264-44-5
包装与价格:
包装价格(元)
500mg电议
1g电议
5g电议

产品介绍
Cas No.73264-44-5
别名蔗糖八硫酸酯钾
Canonical SMILESO=S(O[C@H]1[C@H](OS(=O)([O-])=O)[C@@H](COS(=O)([O-])=O)O[C@H](O[C@]2(COS(=O)([O-])=O)O[C@H](COS(=O)([O-])=O)[C@@H](OS(=O)([O-])=O)[C@@H]2OS(=O)([O-])=O)[C@@H]1OS(=O)([O-])=O)([O-])=O.[K+].[K+].[K+].[K+].[K+].[K+].[K+].[K+]
分子式C12H14O35S8•8K
分子量1287.5
溶解度Water: 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium against acid injury. It can bind to exosite II of thrombin (KD = ~1.4 µM) and inhibit its catalytic activity (IC50 = 4.5 µM) and, as such, has been used as a surrogate for heparin. Furthermore, SOS has been shown to inhibit tumor growth in mouse melanoma and lung carcinoma models by preventing fibroblast growth factor 2 (FGF-2) binding to endothelial cells and also by removing any pre-bound FGF-2 from these cells (IC50 = ~2 µg/ml).