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ZINC13466751
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ZINC13466751图片
CAS NO:117953-17-0
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
ZINC13466751 是一种 HIF-1α/von Hippel-Lindau 相互作用的有效抑制剂,IC50 值为 2.0 ?M。
Cas No.117953-17-0
Canonical SMILESO=C(N(C1=CC=CC=C1)N=C/2C)C2=N/NC3=CC=C(N4CCOCC4)C=C3
分子式C20H21N5O2
分子量363.41
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

ZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 µM[1]. IC50: 2.0 µM (HIF-1α/von Hippel-Lindau)[1]

[1]. Xue X, et al. Discovery of novel inhibitors disrupting HIF-1α/von Hippel-Lindau interaction through shape-based screening and cascade docking. PeerJ. 2016 Dec 15;4:e2757.