您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > SB 772077B dihydrochloride
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
SB 772077B dihydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SB 772077B dihydrochloride图片
CAS NO:607373-46-6
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
SB 772077B dihydrochloride 是一种基于氨基呋喃的 Rho 激酶 (ROCK) 抑制剂,对 ROCK1 和 ROCK2 的 IC50 分别为 5.6 nM 和 6 nM。
Cas No.607373-46-6
化学名(S)-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl)(3-aminopyrrolidin-1-yl)methanone dihydrochloride
Canonical SMILESCCN1C2=C(C(N3CC[C@@](N)([H])C3)=O)C=NC=C2N=C1C4=NON=C4N.Cl.Cl
分子式C15H18N8O2.2HCl
分子量415.28
溶解度<41.53mg/ml in Water;<41.53mg/ml in DMSO
储存条件Desiccate at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

SB-772077B dihydrochloride is an aminofurazan-based Rho kinase (ROCK) inhibitor with IC50s of 5.6 nM and 6 nM toward ROCK1 and ROCK2, respevtively[1].

References:
[1]. Doe C, et al. Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities. J Pharmacol Exp Ther. 2007 Jan;320(1):89-98.