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ROCK-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ROCK-IN-1图片
CAS NO:934387-35-6
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍

ROCK-IN-1是一种有效的ROCK抑制剂,能够抑制ROCK2的活性,IC50值为1.2nM。

Cas No.934387-35-6
Canonical SMILESO=C(C1=CC(C2=CC=C(F)C=C2)=C(C(N)C)C=C1)NC3=CC=NC=C3
分子式C20H18FN3O
分子量335.37
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2.

ROCK-IN-1 shows potent cellular efficacy, with an EC50 of 200 nM[1].

[1]. Boland S, et al. 3-[2-(Aminomethyl)-5-[(pyridin-4-yl)carbamoyl]phenyl] benzoates as soft ROCK inhibitors. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6442-6.