| CAS NO: | 30220-46-3 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 50mg | 电议 |
| Cas No. | 30220-46-3 |
| 别名 | 巨大戟醇; (-)-Ingenol |
| Canonical SMILES | O[C@@]([C@@H](C(CO)=C[C@@]1([H])[C@H](C2(C)C)[C@H]2C3)O)([C@H]4O)[C@]([C@@H]3C)(C=C4C)C1=O |
| 分子式 | C20H28O5 |
| 分子量 | 348.43 |
| 溶解度 | DMSO : 100 mg/mL (287.00 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Ingenol is a PKC activator, with a Ki of 30 μM, with antitumor activity. Ingenol is a PKC activator, with a Ki of 30 μM. Ingenol induces ornithine decarboxylase activity (1, 3 mM), and causes morphological changes (1 mM) in primary mouse epidermal keratinocytes. Ingenol (125 μM, 250 μM, 500 μM, 1 mM) also inhibits cell-cell communication[1]. [1]. Hasler CM, et al. Specific binding to protein kinase C by ingenol and its induction of biological responses. Cancer Res. 1992 Jan 1;52(1):202-8. |
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