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N-Acetylpuromycin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
N-Acetylpuromycin图片
CAS NO:22852-13-7
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Cas No.22852-13-7
Canonical SMILESO[C@H]([C@@H]1NC([C@@H](NC(C)=O)CC2=CC=C(OC)C=C2)=O)[C@@H](O[C@@H]1CO)N3C(N=CN=C4N(C)C)=C4N=C3
分子式C24H31N7O6
分子量513.6
溶解度DMF: 55 mg/ml,DMSO: 70 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-Acetylpuromycin is a non-ribotoxic form of the antibiotic puromycin that is formed in puromycin-resistant S. alboniger that endogenously express puromycin-acetyltransferase. In AD293(Pr) cells that express puromycin-N-acetyltransferase, the enzyme responsible for the biosynthesis of N-acetylpuromycin, puromycin application induces downregulation of the negative regulators of TGF-β signalling SnoN and Ski without activating MAPK or inhibition of protein synthesis.