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ROCK inhibitor-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ROCK inhibitor-2图片
CAS NO:1127308-52-4
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
ROCK inhibitor-2 是一种选择性 ROCK1 和 ROCK2 双抑制剂,IC50 值分别为 17 nM 和2 nM。
Cas No.1127308-52-4
Canonical SMILESO=C(N[C@H](C)C1=CC=CC(OC)=C1)C(C=C2)=CC=C2C3=CC=NC=C3
分子式C21H20N2O2
分子量332.4
溶解度DMSO: 250 mg/mL (752.11 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

ROCK inhibitor-2 is a selective dual ROCK1 and ROCK2 inhibitor with IC50s of 17 nM and 2 nM, respectively[1]. ROCK1|17 nM (IC50)|ROCK2|2 nM (IC50)

[1]. Hobson AD, et al. Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based DrugDesign. J Med Chem. 2018 Dec 27;61(24):11074-11100.