GDC-0339是Pim激酶抑制剂,作用于BaF3PIM1时,IC50为43.6nM。
| Cas No. | 1428569-85-0 |
| Canonical SMILES | FC1=CC=CC(F)=C1C2=NC(C(NC3=C(N4CC[C@@H](F)[C@H](N)CC4)N(C)N=C3)=O)=C(N)S2 |
| 分子式 | C20H22F3N7OS |
| 分子量 | 465.5 |
| 溶解度 | DMSO : ≥ 52 mg/mL (111.71 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | GDC-0339 is a Pim kinase inhibitor with IC50 of 43.6 nM for BaF3 PIM1.IC50 value: 43.6 nM (for BaF3 PIM1), 0.04 nM (Ki, for PIM1 LC-3K)Target: Pim |
m.cnreagent.com