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Angoline hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Angoline hydrochloride图片
CAS NO:1071676-04-4
包装:5mg
市场价:1620元

产品介绍
Angolinehydrochloride是一种有效的选择性的IL6/STAT3信号通路抑制剂,IC50为11.56μM。Angolinehydrochloride抑制STAT3磷酸化及其靶基因表达,并抑制癌细胞增殖。
Cas No.1071676-04-4
Canonical SMILESCN1C2=C3C(C=C4OCOC4=C3)=CC=C2C5=C(C(OC)=C(OC)C=C5)C1OC.[H]Cl
分子式C22H22ClNO5
分子量415.87
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation[1].

[1]. Jiawei Liu, et al. Angoline: a selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum. Phytomedicine. Jul-Aug 2014;21(8-9):1088-91.