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Stafib-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Stafib-1图片
CAS NO:1688703-26-5
包装:5mg
市场价:1980元

产品介绍
Stafib-1 是首个选择性的 STAT5b SH2 结构域的抑制剂,其 Ki 值为 44 nM,IC50 值为 154 nM。
Cas No.1688703-26-5
分子式C26H24N2O11P2
分子量602.42
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Stafib-1 is the first selective inhibitor of the STAT5b SH2 domain, with a Ki of 44 nM and an IC50 of 154 nM[1].

Stafib-1 is the first small molecule which inhibits the STAT5b SH2 domain with more than 50-fold selectivity over STAT5a[1].

[1]. Nagarajan Elumalai, et al. Rational development of Stafib-2: a selective, nanomolar inhibitor of the transcription factor STAT5b. Sci Rep. 2017 Apr 11;7(1):819.