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Hexapeptide-11(acetate)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Hexapeptide-11(acetate)图片
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
A synthetic hexapeptide
Canonical SMILESN[C@H](C(N[C@@H](C(C)C)C(N[C@@H](C)C(N1CCC[C@H]1C(N[C@@H](CC2=CC=CC=C2)C(N3[C@H](C(O)=O)CCC3)=O)=O)=O)=O)=O)CC4=CC=CC=C4.CC(O)=O
分子式C36H48N6O7.XC2H4O2
分子量676.8
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Hexapeptide-11 is a synthetic hexapeptide.1 Hexapeptide-11 (5% v/v) increases the expression of the antioxidant genes Nrf2, Keap1, NQO1, and TXNRD1 and decreases hydrogen peroxide-induced senescence of IMR-90 human lung fibroblasts in vitro. Hexapeptide-11 (5% v/v) increases the activity of matrix metalloproteinase-2 (MMP-2) and MMP-9 and the proteasome peptidases LLVY/β5 and LLE/β1 in IMR-90 cells in vitro and reduces the migration of IMR-90 cells in a scratch wound assay.

|1. Sklirou, A.D., Ralli, M., Dominguez, M., et al. Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts. Redox Biol. 5, 205-215 (2015).