您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > TCH-165
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
TCH-165
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TCH-165图片
CAS NO:1446350-60-2
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
TCH-165 是蛋白酶体组装的小分子调节剂,可增加 20S 水平并促进 20S 介导的蛋白质降解。
Cas No.1446350-60-2
Canonical SMILESO=C([C@]1(C2=CC=CC=C2)N=C(C3=CC=C(OC)C=C3)N(CC4=CC=CC=C4)[C@@H]1C5=CC=C(NCC6=CC=CC=C6)C=C5)OCC
分子式C39H37N3O3
分子量595.73
溶解度DMSO: 250 mg/mL (419.65 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

TCH-165 is a small molecule modulator of proteasome assembly, which increases 20S levels and facilitates 20S-mediated protein degradation[1].

[1]. Njomen E, et al. Small Molecule Modulation of Proteasome Assembly. Biochemistry. 2018 Jul 17;57(28):4214-4224.